Clostridium Chauvoei Bacterin.

CFR · 2024-01-01 · US · Title 9

Clostridium Chauvoei Bacterin shall be produced from a culture of (a) (b) (c) (1) Each of at least 8 but not more than 10 guinea pigs, each weighing 300 to 500 grams, shall be injected subcutaneously with a guinea pig dose. A second guinea pig dose shall be injected 21 to 23 days after the first dose. Each guinea pig dose shall be one-fifth of the dose recommended on the label for a calf. (2) (3) For a valid test, at least 80 percent of the controls shall die within the 3 day post-challenge observation period. If this requirement is met, the results of the potency test shall be evaluated according to the following table:

official document · source cfr-2024 · id 9:§ 113.106