Avian Encephalomyelitis Vaccine, Killed Virus.

CFR · 2024-01-01 · US · Title 9

Avian Encephalomyelitis Vaccine (Killed Virus) shall be prepared from virus-bearing tissues or fluids obtained from embryonated chicken eggs. Each serial shall meet the general requirements prescribed in § 113.200 and the requirements prescribed in this section. Any serial found unsatisfactory by a prescribed test shall not be released. (a) (2) An inactivation test for viable avian encephalomyelitis (AE) virus shall be conducted on each serial. The test shall be conducted using susceptible chicken embryos: (i) (ii) (b) (1) At least 28 days post-injection, the vaccinates and the controls shall be challenged intramuscularly with a virulent AE virus and the chickens observed each day for 21 days. (2) If at least 80 percent of the controls do not show clinical signs of or die from AE infection, the test is a No Test and may be repeated. (3) If at least 80 percent of the vaccinates do not remain normal, the serial is unsatisfactory.

official document · source cfr-2024 · id 9:§ 113.208